Biomarkers of oxidative stress and its association with the urinary reducing capacity in bus maintenance workers.

ABSTRACT:

Background

Exposure to particles (PM) induces adverse health effects (cancer, cardiovascular and pulmonary diseases). A key-role in these adverse effects seems to be played by oxidative stress, which is an excess of reactive oxygen species relative to the amount of reducing species (including antioxidants), the first line of defense against reactive oxygen species. The aim of this study was to document the oxidative stress caused by exposure to respirable particles in vivo, and to test whether exposed workers presented changes in their urinary levels for reducing species.

Methods

Bus depot workers (n = 32) exposed to particles and pollutants (respirable PM4, organic and elemental carbon, particulate metal content, polycyclic aromatic hydrocarbons, NOx, O3) were surveyed over

SUBMITTER: Sauvain JJ 

PROVIDER: S-EPMC3135575 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature