Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review.

ABSTRACT:

Background

Paget's disease is a rare skin disorder occurring in the breast (mammary) or in the groin, genital, peri-anal and axillary regions (extra-mammary). Typical treatment involves surgical excision, which in the case of extra-mammary Paget's disease, can lead to significant morbidity. Photodynamic therapy (PDT) which uses a topical or intravenous photosensitizing agent that is activated by a light source to ablate abnormal tissue, offers a minimally invasive alternative. The purpose of this study was to assess the effectiveness of photodynamic therapy in the treatment of Paget's disease.

Methods

Following Cochrane guidelines, a comprehensive systematic review of all clinical studies and reports examining the use of PDT for mammary and extra-mammary Paget's disease was

SUBMITTER: Nardelli AA 

PROVIDER: S-EPMC3141658 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature