PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus genome.

ABSTRACT:

Background

Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few thousand sequences are to be included, analyzing the phylogenetic relationships among them becomes a challenging task. The recent frequent outbreaks of influenza A viruses have resulted in the rapid accumulation of corresponding genome sequences. Currently, there are more than 7500 influenza A virus genomes in the database. There are no efficient ways of representing this huge data set as a whole, thus preventing a further understanding of the diversity of the influenza A virus genome.

Results

Here we present a new algorithm, "PhyloMap", which combines ordination, vector quantization, and phylogenet

SUBMITTER: Zhang J 

PROVIDER: S-EPMC3142226 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature