Dairy attentuates oxidative and inflammatory stress in metabolic syndrome.

ABSTRACT:

Background

Oxidative and inflammatory stress are elevated in obesity and are further augmented in metabolic syndrome. We showed previously that dairy components suppress the adipocyte- and macrophage-mediated generation of reactive oxygen species and inflammatory cytokines and systemic oxidative and inflammatory biomarkers in obesity.

Objective

The objective of this study was to determine the early (7 d) and sustained (4 and 12 wk) effects of adequate-dairy (AD) compared with low-dairy (LD) diets in subjects with metabolic syndrome.

Design

Forty overweight and obese adults with metabolic syndrome were randomly assigned to receive AD (3.5 daily servings) or LD (<0.5 daily servings) weight-maintenance diets for 12 wk. Oxidative and inflammatory biomarkers were assessed

SUBMITTER: Stancliffe RA 

PROVIDER: S-EPMC3142721 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature