A genetic linkage map and comparative mapping of the prairie vole (Microtus ochrogaster) genome.

ABSTRACT:

Background

The prairie vole (Microtus ochrogaster) is an emerging rodent model for investigating the genetics, evolution and molecular mechanisms of social behavior. Though a karyotype for the prairie vole has been reported and low-resolution comparative cytogenetic analyses have been done in this species, other basic genetic resources for this species, such as a genetic linkage map, are lacking.

Results

Here we report the construction of a genome-wide linkage map of the prairie vole. The linkage map consists of 406 markers that are spaced on average every 7 Mb and span an estimated ~90% of the genome. The sex average length of the linkage map is 1707 cM, which, like other Muroid rodent linkage maps, is on the lower end of the length distribution of linkage maps reported to

SUBMITTER: McGraw LA 

PROVIDER: S-EPMC3143096 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature