Dealing with dietary measurement error in nutritional cohort studies.

ABSTRACT: Dietary measurement error creates serious challenges to reliably discovering new diet-disease associations in nutritional cohort studies. Such error causes substantial underestimation of relative risks and reduction of statistical power for detecting associations. On the basis of data from the Observing Protein and Energy Nutrition Study, we recommend the following approaches to deal with these problems. Regarding data analysis of cohort studies using food-frequency questionnaires, we recommend 1) using energy adjustment for relative risk estimation; 2) reporting estimates adjusted for measurement error along with the usual relative risk estimates, whenever possible (this requires data from a relevant, preferably internal, validation study in which participants report intakes using both th

SUBMITTER: Freedman LS 

PROVIDER: S-EPMC3143422 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature