Intervertebral disc health preservation after six months of spinal growth modulation.

ABSTRACT:

Background

Spinal growth modulation has been proposed as a non-fusion strategy for treatment of idiopathic scoliosis, although the effect of this treatment modality on intervertebral disc health has not been evaluated in detail. The objectives of this in vivo study were to assess the creation of three-dimensional spinal deformity during six months of growth modulation compared with that in sham-surgery controls, and to compare, with use of magnetic resonance imaging (MRI), gross morphological, histological, and biochemical analyses, disc health between control animals and animals treated with a spinal tether.

Methods

Six immature Yucatan mini-pigs underwent anterior spinal instrumentation with vertebral screws connected by a polyethylene tether over four consecutive thoracic

SUBMITTER: Upasani VV 

PROVIDER: S-EPMC3143582 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature