Current therapeutic strategies for invasive and metastatic bladder cancer.

ABSTRACT:

Background

Bladder cancer is one of the most common cancers in Europe, the United States, and Northern African countries. Muscle-invasive bladder cancer is an aggressive epithelial tumor, with a high rate of early systemic dissemination. Superficial, noninvasive bladder cancer can most often be cured; a good proportion of invasive cases can also be cured by a combined modality approach of surgery, chemotherapy, and radiation. Recurrences are common and mostly manifest as metastatic disease. Those with distant metastatic disease can sometime achieve partial or complete remission with combination chemotherapy.

Recent developments

Better understanding of the biology of the disease has led to the incorporation of molecular and genetic features along with factors such as tumor gr

SUBMITTER: Vishnu P 

PROVIDER: S-EPMC3143909 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature