Project description:Mammographic breast cancer screening is effective in reducing breast cancer mortality. Nevertheless, several limitations are known. The objective of this study was to identify circulating microRNAs (miRs) ratios associated with BC in women attending mammography screening. A nested case-control study was conducted within the ANDROMEDA cohort (women of age 46-67 attending BC screening in northern Italy), where pre-diagnostic plasma samples, information on life-styles and common BC risk factors were collected. Small RNA sequencing was carried out on plasma samples from 65 cases and 66 controls. miR-ratios associated with BC were selected by two-sample Wilcoxon test and lasso logistic regression. Subsequent assessment by RT-qPCR of the miRs contained in the selected miR-ratios was carried out as a platform validation. Penalized logistic regression was further applied to candidate miR-ratios alone, or in combination with non-molecular factors, to build a diagnostic model.

2023-07-26 | GSE210329 | GEO

Age and Sex Ratios in a High-Density Wild Red-Legged Partridge Population.

Project description: Not available

| S-EPMC4979962 | biostudies-literature

Conization and healthcare use: a population-based register study.

Project description: Not available

| S-EPMC6365254 | biostudies-literature

Bayesian Reconstruction of Two-Sex Populations by Age: Estimating Sex Ratios at Birth and Sex Ratios of Mortality.

Project description: Not available

| S-EPMC4657758 | biostudies-literature