Sex differences in the incidence and case fatality rates from hemorrhagic fever with renal syndrome in China, 2004-2008.

ABSTRACT:

Background

Differences between male and female individuals in response to infectious diseases are an overlooked global health problem.

Methods

The relationship between sex and disease outcome was examined in populations of patients with hemorrhagic fever with renal syndrome (HFRS) in mainland China, where most cases of hantavirus exposure occur. HFRS in China is diagnosed on the basis of symptoms and is confirmed with serological testing. The geographical distribution, incidence, and case fatality rates (CFRs) of HFRS in China were estimated and compared by patient sex and age. In a subset of patients with HFRS, clinical manifestations of HFRS were assessed using latent class analysis and compared by sex.

Results

There were 80,671 HFRS cases reported during the period

SUBMITTER: Klein SL 

PROVIDER: S-EPMC3146012 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature