Genome-wide deficiency screen for the genomic regions responsible for heat resistance in Drosophila melanogaster.

ABSTRACT:

Background

Temperature adaptation is one of the most important determinants of distribution and population size of organisms in nature. Recently, quantitative trait loci (QTL) mapping and gene expression profiling approaches have been used for detecting candidate genes for heat resistance. However, the resolution of QTL mapping is not high enough to examine the individual effects of various genes in each QTL. Heat stress-responsive genes, characterized by gene expression profiling studies, are not necessarily responsible for heat resistance. Some of these genes may be regulated in association with the heat stress response of other genes.

Results

To evaluate which heat-responsive genes are potential candidates for heat resistance with higher resolution than previous QTL mappi

SUBMITTER: Takahashi KH 

PROVIDER: S-EPMC3146426 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature