Global proteomics analysis of testis and ovary in adult zebrafish (Danio rerio).

ABSTRACT: The molecular mechanisms controlling sex determination and differentiation in zebrafish (Danio rerio) are largely unknown. A genome-wide analysis may provide comprehensive insights into the processes involved. The mRNA expression in zebrafish gonads has been fairly well studied, but much less data on the corresponding protein expression are available, although the proteins are considered to be more relevant markers of gene function. Because mRNA and protein abundances rarely correlate well, mRNA profiles need to be complemented with the information on protein expression. The work presented here analyzed the proteomes of adult zebrafish gonads by a multidimensional protein identification technology, generating the to-date most populated lists of proteins expressed in mature zebrafish gonads

SUBMITTER: Groh KJ 

PROVIDER: S-EPMC3146978 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature