Association of serum phosphate levels with aortic valve sclerosis and annular calcification: the cardiovascular health study.

ABSTRACT:

Objectives

This study was conducted to evaluate mineral metabolism markers as potential risk factors for calcific aortic valve disease.

Background

Mineral metabolism disturbances are common among older people and may contribute to cardiac valvular calcification. Associations of serum mineral metabolism markers with cardiac valvular calcification have not been evaluated in a well-characterized general population of older adults.

Methods

We measured serum levels of phosphate, calcium, parathyroid hormone, and 25-hydroxyvitamin D in 1,938 Cardiovascular Health Study participants who were free of clinical cardiovascular disease and who underwent echocardiographic measurements of aortic valve sclerosis (AVS), mitral annular calcification (MAC), and aortic annular calcifica

SUBMITTER: Linefsky JP 

PROVIDER: S-EPMC3147295 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature