TdaA regulates Tropodithietic acid synthesis by binding to the tdaC promoter region.

ABSTRACT: Silicibacter sp. TM1040, a member of the marine Roseobacter clade, produces the antibiotic and quorum signaling molecule tropodithietic acid (TDA), encoded by tdaABCDEF. Here, we showed that an LysR-type transcriptional regulator, TdaA, is a positive regulator of tdaCDE gene expression and binds to the tdaC promoter region.

SUBMITTER: Geng H 

PROVIDER: S-EPMC3147533 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature