Alternative approaches to assessing intervention effectiveness in randomized trials: application in a colorectal cancer screening study.

ABSTRACT:

Background

Previous analysis of a randomized community-based trial of a multi-component intervention to increase colorectal cancer (CRC) screening among Filipino Americans (n = 548) found significantly higher screening rates in the two intervention groups compared to the control group, when using intent-to-treat analysis and self-reported screening as the outcome. This report describes more nuanced findings obtained from alternative approaches to assessing intervention effectiveness to inform future intervention implementation.

Methods

The effect of the intervention on CRC screening receipt during follow-up was estimated using methods that adjusted for biases due to missing data and self-report and for different combinations of intervention components. Adjustment for self-re

SUBMITTER: Maxwell AE 

PROVIDER: S-EPMC3148350 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature