Comparison between elementary flux modes analysis and 13C-metabolic fluxes measured in bacterial and plant cells.

ABSTRACT:

Background

(13)C metabolic flux analysis is one of the pertinent ways to compare two or more physiological states. From a more theoretical standpoint, the structural properties of metabolic networks can be analysed to explore feasible metabolic behaviours and to define the boundaries of steady state flux distributions. Elementary flux mode analysis is one of the most efficient methods for performing this analysis. In this context, recent approaches have tended to compare experimental flux measurements with topological network analysis.

Results

Metabolic networks describing the main pathways of central carbon metabolism were set up for a bacteria species (Corynebacterium glutamicum) and a plant species (Brassica napus) for which experimental flux maps were available. The stru

SUBMITTER: Beurton-Aimar M 

PROVIDER: S-EPMC3148577 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature