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Monovalent, clickable, uncharged, water-soluble perylenediimide-cored dendrimers for target-specific fluorescent biolabeling.


ABSTRACT: Herein we report the synthesis of water-soluble polyglycerol-dendronized perylenediimides with a single reactive group that undergoes high-yielding click reactions. Single-molecule studies and target-specific biolabeling are reported, including the highly specific labeling of proteins on the surface of living bacterial and mammalian cells.

SUBMITTER: Yang SK 

PROVIDER: S-EPMC3148660 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

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Monovalent, clickable, uncharged, water-soluble perylenediimide-cored dendrimers for target-specific fluorescent biolabeling.

Yang Si Kyung SK   Shi Xinghua X   Park Seongjin S   Doganay Sultan S   Ha Taekjip T   Zimmerman Steven C SC  

Journal of the American Chemical Society 20110614 26


Herein we report the synthesis of water-soluble polyglycerol-dendronized perylenediimides with a single reactive group that undergoes high-yielding click reactions. Single-molecule studies and target-specific biolabeling are reported, including the highly specific labeling of proteins on the surface of living bacterial and mammalian cells. ...[more]

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