Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiency.

ABSTRACT: As organisms adaptively evolve to a new environment, selection results in the improvement of certain traits, bringing about an increase in fitness. Trade-offs may result from this process if function in other traits is reduced in alternative environments either by the adaptive mutations themselves or by the accumulation of neutral mutations elsewhere in the genome. Though the cost of adaptation has long been a fundamental premise in evolutionary biology, the existence of and molecular basis for trade-offs in alternative environments are not well-established. Here, we show that yeast evolved under aerobic glucose limitation show surprisingly few trade-offs when cultured in other carbon-limited environments, under either aerobic or anaerobic conditions. However, while adaptive clones consist

SUBMITTER: Wenger JW 

PROVIDER: S-EPMC3150441 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature