Addressing inter-gene heterogeneity in maximum likelihood phylogenomic analysis: yeasts revisited.

ABSTRACT: Phylogenomic approaches to the resolution of inter-species relationships have become well established in recent years. Often these involve concatenation of many orthologous genes found in the respective genomes followed by analysis using standard phylogenetic models. Genome-scale data promise increased resolution by minimising sampling error, yet are associated with well-known but often inappropriately addressed caveats arising through data heterogeneity and model violation. These can lead to the reconstruction of highly-supported but incorrect topologies. With the aim of obtaining a species tree for 18 species within the ascomycetous yeasts, we have investigated the use of appropriate evolutionary models to address inter-gene heterogeneities and the scalability and validity of supermatrix

SUBMITTER: Hess J 

PROVIDER: S-EPMC3151265 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature