Ethnic differences in arterial wave reflections and normative equations for augmentation index.

ABSTRACT: Data regarding ethnic differences in wave reflections, which markedly affect the central pressure profile, are very limited. Furthermore, because age, heart rate, and body height are strong determinants of augmentation index, relating single measurements to normative data (in which augmentation index values correspond with average population values of its determinants) is challenging. We studied subject-level data from 10 550 adults enrolled in large population-based studies. In a healthy reference sample (n=3497), we assessed ethnic differences in augmentation index (ratio of second/first systolic peaks) and generated equations for adjusted z scores, allowing for a standardized comparison between individual augmentation index measurements and the normative population mean from subjects of

SUBMITTER: Chirinos JA 

PROVIDER: S-EPMC3151727 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature