Cross-couplings between benzylic and aryl halides "on water": synthesis of diarylmethanes.

ABSTRACT: A remarkably simple entry to unsymmetrical diarylmethanes has been developed that relies on an in situ organozinc-mediated, palladium-catalyzed cross-coupling. Thus, by mixing a benzyl and aryl halide together in the presence of Zn metal and a Pd catalyst, diarylmethanes are formed at room temperature without assistance by a surfactant; hence, "on water".

SUBMITTER: Duplais C 

PROVIDER: S-EPMC3152455 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature