Self-perceived quality of life predicts mortality risk better than a multi-biomarker panel, but the combination of both does best.

ABSTRACT:

Background

Associations between measures of subjective health and mortality risk have previously been shown. We assessed the impact and comparative predictive performance of a multi-biomarker panel on this association.

Methods

Data from 4,261 individuals aged 20-79 years recruited for the population-based Study of Health in Pomerania was used. During an average 9.7 year follow-up, 456 deaths (10.7%) occurred. Subjective health was assessed by SF-12 derived physical (PCS-12) and mental component summaries (MCS-12), and a single-item self-rated health (SRH) question. We implemented Cox proportional-hazards regression models to investigate the association of subjective health with mortality and to assess the impact of a combination of 10 biomarkers on this association. Variable

SUBMITTER: Haring R 

PROVIDER: S-EPMC3152941 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature