Ontology highlight
ABSTRACT:
SUBMITTER: Schaaf CP
PROVIDER: S-EPMC3153303 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Human molecular genetics 20110530 17
Autism spectrum disorders (ASDs) are a heterogeneous group of neuro-developmental disorders. While significant progress has been made in the identification of genes and copy number variants associated with syndromic autism, little is known to date about the etiology of idiopathic non-syndromic autism. Sanger sequencing of 21 known autism susceptibility genes in 339 individuals with high-functioning, idiopathic ASD revealed de novo mutations in at least one of these genes in 6 of 339 probands (1. ...[more]