Determinants of work disability in patients with systemic sclerosis: a longitudinal study of the GENISOS cohort.

ABSTRACT:

Objectives

To determine the prevalence, correlates, and predictors of work disability (WD) in the Genetics versus ENvironment In Scleroderma Outcome Study (GENISOS). We hypothesized that WD in systemic sclerosis (SSc) is a function of demographic, clinical, and psychosocial factors.

Methods

Patients enrolled in the GENISOS cohort were subdivided in 3 groups: work disabled, working, and retired or homemakers. The latter group (n = 29) was excluded from further analysis. We used logistic regression analysis with a forward hierarchical variable selection strategy to investigate the independent correlates of WD at enrollment. Cox regression proportional Hazard's model with a similar variable selection strategy was utilized to determine the predictors of WD in those working at en

SUBMITTER: Sharif R 

PROVIDER: S-EPMC3153604 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature