Carotid-wall intima-media thickness and cardiovascular events.

ABSTRACT:

Background

Intima-media thickness of the walls of the common carotid artery and internal carotid artery may add to the Framingham risk score for predicting cardiovascular events.

Methods

We measured the mean intima-media thickness of the common carotid artery and the maximum intima-media thickness of the internal carotid artery in 2965 members of the Framingham Offspring Study cohort. Cardiovascular-disease outcomes were evaluated for an average follow-up of 7.2 years. Multivariable Cox proportional-hazards models were generated for intima-media thickness and risk factors. We evaluated the reclassification of cardiovascular disease on the basis of the 8-year Framingham risk score category (low, intermediate, or high) after adding intima-media thickness values.

Results

SUBMITTER: Polak JF 

PROVIDER: S-EPMC3153949 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature