Morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria: a randomised trial.

ABSTRACT:

Background

Interventions that reduce exposure to malaria infection may lead to delayed malaria morbidity and mortality. We investigated whether intermittent preventive treatment of malaria in children (IPTc) was associated with an increase in the incidence of malaria after cessation of the intervention.

Methods

An individually randomised, trial of IPTc, comparing three courses of sulphadoxine pyrimethamine (SP) plus amodiaquine (AQ) with placebos was implemented in children aged 3-59 months during the 2008 malaria transmission season in Burkina Faso. All children in the trial were given a long lasting insecticide treated net; 1509 children received SP+AQ and 1505 received placebos. Passive surveillance for malaria was maintained until the end of the subsequent malaria transm

SUBMITTER: Konate AT 

PROVIDER: S-EPMC3155539 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature