Driving and driven architectures of directed small-world human brain functional networks.

ABSTRACT: Recently, increasing attention has been focused on the investigation of the human brain connectome that describes the patterns of structural and functional connectivity networks of the human brain. Many studies of the human connectome have demonstrated that the brain network follows a small-world topology with an intrinsically cohesive modular structure and includes several network hubs in the medial parietal regions. However, most of these studies have only focused on undirected connections between regions in which the directions of information flow are not taken into account. How the brain regions causally influence each other and how the directed network of human brain is topologically organized remain largely unknown. Here, we applied linear multivariate Granger causality analysis (GCA

SUBMITTER: Yan C 

PROVIDER: S-EPMC3155571 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature