Punctate white matter lesions in infants: new insights using susceptibility-weighted imaging.

ABSTRACT:

Introduction

Punctate white matter lesions (PWML) are recognized with magnetic resonance imaging (MRI) as hypersignal on T1-weighted imaging and hyposignal on T2-weighted imaging. Our aim was to assess how often a hemorrhagic component was present in PWML using susceptibility-weighted imaging (SWI).

Methods

Seventeen preterm (gestational age, 25-34 weeks) and seven full-term infants (age at MRI, 37-42 weeks) with PWML were included. Seven preterm infants had sequential MRIs. PWML were diagnosed with conventional MRI and compared with SWI, where signal loss is suggestive of hemorrhage. The pattern of associated brain lesions was taken into account, and the percentage of lesions with signal loss on SWI was calculated for each infant.

Results

A significantly higher perce

SUBMITTER: Niwa T 

PROVIDER: S-EPMC3156303 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature