Dopamine polymorphisms and depressive symptoms predict foods intake. Results from a nationally representative sample.

ABSTRACT: Depression and variation in dopamine related genes have both independently been associated with food consumption. Depressive symptoms could synergistically interact with genetic variation to influence food intake. We examined the interaction between high depressive symptoms and functional polymorphisms of dopamine transporter (SLC6A3), monoamine oxidase A (MAOA), dopamine receptor D2 (DRD2) and dopamine receptor D4 (DRD4) on intake of high-calorie sweet, high-calorie non-sweet, and low-calorie foods in the National Longitudinal Study of Adolescent Health (Add Health). Multivariate linear regression analyses were used to examine main effects of gene and depression symptoms and their interaction (genotype-by-high depression symptoms) on food categories. Applying a false discovery rate criter

SUBMITTER: Agurs-Collins T 

PROVIDER: S-EPMC3156384 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature