Preclinical atherosclerosis due to HIV infection: carotid intima-medial thickness measurements from the FRAM study.

ABSTRACT:

Background

Cardiovascular disease (CVD) is an increasing cause of morbidity and mortality in HIV-infected patients. However, it is controversial whether HIV infection contributes to accelerated atherosclerosis independent of traditional CVD risk factors.

Methods

Cross-sectional study of HIV-infected participants and controls without pre-existing CVD from the study of Fat Redistribution and Metabolic Change in HIV Infection (FRAM) and the Multi-Ethnic Study of Atherosclerosis (MESA). Preclinical atherosclerosis was assessed by carotid intima-medial thickness (cIMT) measurements in the internal/bulb and common regions in HIV-infected participants and controls after adjusting for traditional CVD risk factors.

Results

For internal carotid, mean IMT was 1.17 +/- 0.50 mm fo

SUBMITTER: Grunfeld C 

PROVIDER: S-EPMC3156613 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature