Effects of a novel formulation of fluocinonide 0.1% cream on skin barrier function in atopic dermatitis.

ABSTRACT:

Objective

To determine the effect a novel formulation of fluocinonide cream on skin barrier function in subjects with atopic dermatitis.

Design

The authors performed an open-label, investigator-blinded, side-by-side, controlled trial examining skin barrier function before and after a two-week course of a class I, super-potent topical steroid.

Setting

Outpatient university-based dermatology clinic in Portland, OR.

Subjects

Twenty-five subjects aged 12 or older with a diagnosis of moderate, severe, or very severe AD were recruited for this study.

Intervention

Fluocinonide 0.1% cream, a novel formulation of a class I super-potent topical steroid was applied to all affected areas, except a control site, once daily for two weeks or until clear. The control ta

SUBMITTER: Woods MT 

PROVIDER: S-EPMC3156681 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature