Silanol: a traceless directing group for Pd-catalyzed o-alkenylation of phenols.

ABSTRACT: A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

SUBMITTER: Huang C 

PROVIDER: S-EPMC3156791 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature