Expedient synthesis of N-acyl anthranilamides and β-enamine amides by the Rh(III)-catalyzed amidation of aryl and vinyl C-H bonds with isocyanates.

ABSTRACT: A Rh(III)-catalyzed protocol for the amidation of anilide and enamide C-H bonds with isocyanates has been developed. This method provides direct and efficient syntheses of N-acyl anthranilamides, enamine amides, and pyrimidin-4-one heterocycles.

SUBMITTER: Hesp KD 

PROVIDER: S-EPMC3158987 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature