Differential effects of paced and unpaced responding on delayed serial order recall in schizophrenia.

ABSTRACT: Working memory for temporal order is a component of working memory that is especially dependent on striatal systems, but has not been extensively studied in schizophrenia. This study was designed to characterize serial order reproduction by adapting a spatial serial order task developed for nonhuman primate studies, while controlling for working memory load and whether responses were initiated freely (unpaced) or in an externally paced format. Clinically stable schizophrenia patients (n=27) and psychiatrically healthy individuals (n=25) were comparable on demographic variables and performance on standardized tests of immediate serial order recall (Digit Span, Spatial Span). No group differences were observed for serial order recall when read sequence reproduction was unpaced. However, schi

SUBMITTER: Hill SK 

PROVIDER: S-EPMC3159860 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature