PromBase: a web resource for various genomic features and predicted promoters in prokaryotic genomes.

ABSTRACT:

Background

As more and more genomes are being sequenced, an overview of their genomic features and annotation of their functional elements, which control the expression of each gene or transcription unit of the genome, is a fundamental challenge in genomics and bioinformatics.

Findings

Relative stability of DNA sequence has been used to predict promoter regions in 913 microbial genomic sequences with GC-content ranging from 16.6% to 74.9%. Irrespective of the genome GC-content the relative stability based promoter prediction method has already been proven to be robust in terms of recall and precision. The predicted promoter regions for the 913 microbial genomes have been accumulated in a database called PromBase. Promoter search can be carried out in PromBase either by speci

SUBMITTER: Rangannan V 

PROVIDER: S-EPMC3160392 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature