Developmental and genetic origins of murine long bone length variation.

ABSTRACT: If we wish to understand whether development influences the rate or direction of morphological evolution, we must first understand the developmental bases of morphological variation within species. However, quantitative variation in adult morphology is the product of molecular and cellular processes unfolding from embryonic development through juvenile growth to maturity. The Atchley-Hall model provides a useful framework for dissecting complex morphologies into their component parts as a way of determining which developmental processes contribute to variation in adult form. We have examined differences in postnatal allometry and the patterns of genetic correlation between age-specific traits for ten recombinant inbred strains of mice generated from an intercross of LG/J and SM/J. Long bon

SUBMITTER: Sanger TJ 

PROVIDER: S-EPMC3160521 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature