Intraocular pressure control and long-term visual field loss in the Collaborative Initial Glaucoma Treatment Study.

ABSTRACT:

Objective

To evaluate the impact of measures of intraocular pressure (IOP) control on progression of visual field (VF) loss during long-term treatment for open-angle glaucoma (OAG).

Design

Longitudinal, randomized clinical trial.

Participants

We included 607 participants with newly diagnosed OAG.

Methods

Study participants were randomly assigned to initial treatment with medications or trabeculectomy, and underwent examination at 6-month intervals. Standardized testing included Goldmann applanation tonometry and Humphrey 24-2 full threshold VFs. Summary measures of IOP control during follow-up included the maximum, mean, standard deviation (SD), range, proportion less than 16, 18, 20, or 22 mmHg, and whether all IOP values were less than each of these 4 cutpoin

SUBMITTER: Musch DC 

PROVIDER: S-EPMC3161134 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature