High rates of all-cause and gastroenteritis-related hospitalization morbidity and mortality among HIV-exposed Indian infants.

ABSTRACT:

Background

HIV-infected and HIV-exposed, uninfected infants experience a high burden of infectious morbidity and mortality. Hospitalization is an important metric for morbidity and is associated with high mortality, yet, little is known about rates and causes of hospitalization among these infants in the first 12 months of life.

Methods

Using data from a prevention of mother-to-child transmission (PMTCT) trial (India SWEN), where HIV-exposed breastfed infants were given extended nevirapine, we measured 12-month infant all-cause and cause-specific hospitalization rates and hospitalization risk factors.

Results

Among 737 HIV-exposed Indian infants, 93 (13%) were HIV-infected, 15 (16%) were on HAART, and 260 (35%) were hospitalized 381 times by 12 months of life. Fifty-s

SUBMITTER: Singh HK 

PROVIDER: S-EPMC3161884 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature