Determination of awareness in patients with severe brain injury using EEG power spectral analysis.

ABSTRACT:

Objective

To determine whether EEG spectral analysis could be used to demonstrate awareness in patients with severe brain injury.

Methods

We recorded EEG from healthy controls and three patients with severe brain injury, ranging from minimally conscious state (MCS) to locked-in-state (LIS), while they were asked to imagine motor and spatial navigation tasks. We assessed EEG spectral differences from 4 to 24 Hz with univariate comparisons (individual frequencies) and multivariate comparisons (patterns across the frequency range).

Results

In controls, EEG spectral power differed at multiple frequency bands and channels during performance of both tasks compared to a resting baseline. As patterns of signal change were inconsistent between controls, we defined a positive r

SUBMITTER: Goldfine AM 

PROVIDER: S-EPMC3162107 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature