BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons.

ABSTRACT:

Background

Visualisation of genome comparisons is invaluable for helping to determine genotypic differences between closely related prokaryotes. New visualisation and abstraction methods are required in order to improve the validation, interpretation and communication of genome sequence information; especially with the increasing amount of data arising from next-generation sequencing projects. Visualising a prokaryote genome as a circular image has become a powerful means of displaying informative comparisons of one genome to a number of others. Several programs, imaging libraries and internet resources already exist for this purpose, however, most are either limited in the number of comparisons they can show, are unable to adequately utilise draft genome sequence data, or require

SUBMITTER: Alikhan NF 

PROVIDER: S-EPMC3163573 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature