Early temporal and spatial regularization of persistent atrial fibrillation predicts termination and arrhythmia-free outcome.

ABSTRACT:

Background

Termination of persistent atrial fibrillation (AF) is a valuable ablation endpoint but is difficult to anticipate. We evaluated whether temporal and spatial indices of AF regularization predict intraprocedural AF termination and outcome.

Objective

The purpose of this study was to test whether temporospatial organization of AF after pulmonary vein isolation (PVI) predicts whether subsequent stepwise ablation will terminate persistent AF or predict outcome.

Methods

In 75 patients with persistent AF, we measured AF cycle length (AFCL), temporal regularity index (TRI, a spectral measure of timing regularity), and spatial regularity index (SRI, cycle-to-cycle variations in spatial vector) between right atrial appendage and proximal and distal coronary sinus befo

SUBMITTER: Forclaz A 

PROVIDER: S-EPMC3163722 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature