Arterial spin-labeling MRI can identify the presence and intensity of collateral perfusion in patients with moyamoya disease.

ABSTRACT:

Background and purpose

Determining the presence and adequacy of collateral blood flow is important in cerebrovascular disease. Therefore, we explored whether a noninvasive imaging modality, arterial spin labeling (ASL) MRI, could be used to detect the presence and intensity of collateral flow using digital subtraction angiography (DSA) and stable xenon CT cerebral blood flow as gold standards for collaterals and cerebral blood flow, respectively.

Methods

ASL and DSA were obtained within 4 days of each other in 18 patients with Moyamoya disease. Two neurointerventionalists scored DSA images using a collateral grading scale in regions of interest corresponding to ASPECTS methodology. Two neuroradiologists similarly scored ASL images based on the presence of arterial transit ar

SUBMITTER: Zaharchuk G 

PROVIDER: S-EPMC3164217 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature