Total synthesis of herboxidiene/GEX 1A.

ABSTRACT: A convergent enantioselective synthesis of herboxidiene/GEX 1A (1) is described that features a double stereodifferentiating crotylation, [4 + 2] annulation, and a silicon-based sp2-sp2 cross-coupling to assemble the conjugated diene.

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC3164305 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature