Empirically derived subtypes of opioid use and related behaviors.

ABSTRACT:

Aims

To identify and validate homogeneous subtypes of opioid use and related behaviors.

Design

Family-based and case-control genetic studies of opioid and/or cocaine dependence.

Settings

Clinical and general community samples from Connecticut, Massachusetts, Pennsylvania and South Carolina.

Participants

A total of 4061 individuals (2003 individuals from 835 families and 2058 unrelated individuals) recruited to participate in genetic studies.

Measurements

The computer-assisted Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) was used to assess participants' demographics, medical history, substance use behaviors and disorders and other psychiatric disorders.

Findings

Five homogeneous subtypes were identified, which differed on

SUBMITTER: Chan G 

PROVIDER: S-EPMC3164489 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature