Depressive symptom trajectory predicts 1-year health-related quality of life in patients with heart failure.

ABSTRACT:

Background

One-third of patients with heart failure (HF) experience depressive symptoms that adversely affect health-related quality of life (HRQOL). We aimed to describe depressive symptom trajectory and determine whether a change in depressive symptoms predicts subsequent HRQOL.

Methods and results

The sample consisted of 256 inpatients and outpatients with HF. Depressive symptoms were measured at baseline and 3 or 6 months with the Patient Health Questionnaire (PHQ-9). The Minnesota Living with HF Questionnaire was used to assess HRQOL at baseline, 3 to 6 months, and 1 year. Based on baseline and 3- to 6-month PHQ-9 scores, patients were categorized as depressive symptom-free (64%), depressive symptoms improved (15%), depressive symptoms developed (6%), or persistent depr

SUBMITTER: Dekker RL 

PROVIDER: S-EPMC3164519 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature