Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling.

ABSTRACT:

Background

Bacterial nitrogen fixation is the biological process by which atmospheric nitrogen is uptaken by bacteroids located in plant root nodules and converted into ammonium through the enzymatic activity of nitrogenase. In practice, this biological process serves as a natural form of fertilization and its optimization has significant implications in sustainable agricultural programs. Currently, the advent of high-throughput technology supplies with valuable data that contribute to understanding the metabolic activity during bacterial nitrogen fixation. This undertaking is not trivial, and the development of computational methods useful in accomplishing an integrative, descriptive and predictive framework is a crucial issue to decoding the principles that regulated the metaboli

SUBMITTER: Resendis-Antonio O 

PROVIDER: S-EPMC3164627 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature