Total synthesis of bryostatin 7 via C-C bond-forming hydrogenation.

ABSTRACT: The marine macrolide bryostatin 7 is prepared in 20 steps (longest linear sequence) and 36 total steps with five C-C bonds formed using hydrogenative methods. This approach represents the most concise synthesis of any bryostatin reported, to date.

SUBMITTER: Lu Y 

PROVIDER: S-EPMC3164899 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature