Prevalence of uterine leiomyomas in lymphangioleiomyomatosis.

ABSTRACT:

Objective

To determine the frequency of uterine leiomyomas and hysterectomy in patients with lymphangioleiomyomatosis (LAM), a disease characterized by proliferation of abnormal-appearing smooth muscle-like cells.

Design

Retrospective study.

Setting

Natural history study at the National Institutes of Health.

Patient(s)

456 patients with sporadic LAM and LAM associated with tuberous sclerosis complex (LAM/TSC).

Intervention(s)

Review of records and pelvic computed axial tomography scans.

Main outcome measure(s)

Prevalence of uterine leiomyomas and hysterectomy.

Result(s)

A total of 174 women had uterine leiomyomas (38%). One hundred eighteen were diagnosed by computed tomographic scan and 56 were diagnosed by hysterectomy. Among 323 patients

SUBMITTER: Taveira-Dasilva AM 

PROVIDER: S-EPMC3165169 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature