Equating quantitative emphysema measurements on different CT image reconstructions.

ABSTRACT:

Purpose

To mathematically model the relationship between CT measurements of emphysema obtained from images reconstructed using different section thicknesses and kernels and to evaluate the accuracy of the models for converting measurements to those of a reference reconstruction.

Methods

CT raw data from the lung cancer screening examinations of 138 heavy smokers were reconstructed at 15 different combinations of section thickness and kernel. An emphysema index was quantified as the percentage of the lung with attenuation below -950 HU (EI950). Linear, quadratic, and power functions were used to model the relationship between EI950 values obtained with a reference 1 mm, medium smooth kernel reconstruction and values from each of the other 14 reconstructions. Preferred models

SUBMITTER: Bartel ST 

PROVIDER: S-EPMC3165435 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature