Metal nitrite: a powerful oxidizing reagent.

ABSTRACT: An efficient and simple source of nitroso reagents and their oxidation reactions are described. The combination of a Lewis acid and a metal nitrite was applied to the oxidation of silyl enol ethers. Amino acid and peptide derivatives were easily accessed through in situ C-C bond cleavage of fully substituted silyl enol ethers upon oxidation.

SUBMITTER: Baidya M 

PROVIDER: S-EPMC3166854 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature